Crosses of homozygous HCII-/-animals in the mixed 129/SvJ x C57Bl/6 genetic background produced litters of similar size to those obtained from crosses of heterozygous HCII+/-animals. Thus, homozygous HCII deficiency in both parents is compatible with normal gestation in a mixed genetic background.
Litter size is shown as the mean + 1 SD.
