Douglas M. Tollefsen1, Li He1, Niall S. Colwell2, Pete Lollar3, and Fangru Lian1
1Hematology Division,
Washington University School of Medicine, St. Louis, MO;
2Department of
Pharmacology and Therapeutics, University College, Cork, Ireland;
3Department of
Medicine, Emory University School of Medicine, Atlanta, GA
1. Abstract
2. Introduction
3. Prolongation of the plasma thrombin time
4. Thrombin time of purified fibrinogen
5. Thrombin time of inhibitor-depleted plasma
6. Kinetics of protease inhibition by antithrombin
7. Prolongation of the aPTT of normal plasma
8. aPTT of inhibitor-depleted plasma
9. Effect of the IgG on IXa and Xa clotting times
10. Inhibition of factor VIII activation by thrombin
11. Summary
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